rTMS for the Treatment of Affective Symptoms in Patients Suffering From Dementia

Inclusion Criteria: * Informed consent as documented by their and their proxy's signature (Appendix Informed Consent Form) * Consent for MRI * Age ≥ 65 years * Clinical dementia Rating Scale (CDR) ≥ 1 * NPI-Q Σ (\*Anxiety + \* Apathy/Indifference + \* Dysphoria/Depression) ≥ 3 * Cornell Scale for Depression in Dementia (CSDD) ≥ 10 Exclusion Criteria: * History of schizophrenia, bipolar disorder, schizoaffective disorder * History of macroscopic stroke. * Unstable somatic pathologies * Insufficient collaboration for the rTMS procedure * Drug freeness or drug adjustment as clinically required is not an exclusion criterion. * The proxy refuses to give consent in case of lack of capacity, or in any case where the participant expresses a wish not to participate/continue in the study. * Any contraindications to performing an MRI (cf CRF) and rTMS (aneurysm clips or coils, stents in the neck or brain, deep brain stimulators, electrodes to monitor brain activity, metal implants in the ears and eyes, facial tattoos with metallic or magnetically sensitive ink) procedure