Towards Early Detection of Breast Cancer in High Risk Population

Inclusion Criteria: \- Women with BRCA1/2 genes: * female 18-55 years old, premenopausal * BRCA 1/2 gene carriers * not having any metabolic disorders (e.g., diabetes) * not on any long term medications that may affect lipid metabolism (e.g., statins) * BMI \< 30 Women with breast cancer (no obesity): * females 18-55 years old, premenopausal * confirmed diagnosis of invasive ductal carcinoma of the breast * not having any metabolic disorders (e.g., diabetes) * not on any long term medications that may affect lipid metabolism (e.g., statins) * BMI \< 30 Women with breast cancer (obesity): * BMI \> 30 * otherwise as women with breast cancer Women with obesity: * females 18-55 years old, premenopausal * not having any metabolic disorders (e.g., diabetes) * not on any long term medications that may affect lipid metabolism (e.g., statins) * BMI \> 30 Exclusion Criteria: * females under 18 or over 55 years old, postmenopausal * males * have metabolic disorders (e.g., diabetes) * on long term medications that may affect lipid metabolism (e.g., statins) * contraindicated for MR investigation (poor renal function and metal implants) * (for patients) concurrent cancer in other sites * (for patients) started hormone treatment, chemotherapy or breast surgery * non-English speakers