Trigeminal Neuralgia Electrophysiology

University of Minnesota30 enrolled

Overview

The study intervention is to perform standard somatosensory evoked responses limited to the face during rhizotomy procedures of the gasserian ganglion (trigeminal ganglion) for the treatment of trigeminal neuralgia. The evoked responses will be measured at two locations before and after the clinical rhizotomy including: the standard contralateral scalp (EEG) and at the gasserian ganglion through an FDA-approved recording electrode.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Trigeminal Neuralgia

Interventions

Trigeminal ElectrophysiologyPROCEDURE

This study will pilot and test the feasibility of introducing electrophysiology into the routine rhizotomy procedure by including trigeminal somatosensory evoked potentials (TSEPs) and recording from electrodes at the level of the ganglion.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria (TGN): * Adults of 18 years or older * Scheduled to undergo percutaneous rhizotomy for facial pain Exclusion Criteria (TGN): * Facial pain of unclear origin (i.e. not clearly TGN pain) * Rhizotomy procedure canceled Inclusion Criteria (Healthy controls) * Adults of 18 years or older Exclusion Criteria (Healthy Controls) * Diagnosis or history of facial pain such as TMD or TGN * History of migraine * History of any functional pain disorder: fibromyalgia, IBS, CRPS * Recent chronic pain (within last month) * Unwilling to participate for two hours in lab * Current acute pain

Locations (1)

University of Minnesota

Minneapolis, Minnesota, United States

RECRUITING

Outcomes

Primary Outcomes

Determine the feasibility of measuring trigeminal somatosensory evoked potentials to improve personalized mapping during percutaneous rhizotomy

percentage of consented participants who complete the study

Time frame: 3 years

Central Contacts

Matthew Maple

CONTACT

612-946-1424 maple036@umn.edu

Data from ClinicalTrials.gov

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