This study will assess the effect of almond supplementation on acne and on gut health.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
60g of whole almonds will be consumed daily.
A non-nut snack will be consumed daily.
Integrative Skin Science and Research
Sacramento, California, United States
RECRUITINGTotal lesion count
Number of of inflammatory lesions, and open and closed comedones
Time frame: 20 weeks
Inflammatory lesion count
Number of inflammatory lesions
Time frame: 12 weeks
Inflammatory lesion count
Number of inflammatory lesions
Time frame: 20 weeks
Non-inflammatory lesion count
Number of open and closed comedones
Time frame: 12 weeks
Non-inflammatory lesion count
Number of open and closed comedones
Time frame: 20 weeks
Investigator global assessment (IGA) of acne
Validated scale for global assessment of acne. Scale of 0-4, 4 indicating greater severity.
Time frame: 12 weeks
Investigator global assessment (IGA) of acne
Validated scale for global assessment of acne. Scale of 0-4, 4 indicating greater severity.
Time frame: 20 weeks
Quality of Life Survey
Dermatology quality of life index survey assessment (DQLI). Scale is 0 to 30, the higher the score the greater impairments to quality of life.
Time frame: 12 weeks
Quality of Life Survey
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Dermatology quality of life index survey assessment (DQLI). Scale is 0 to 30, the higher the score the greater impairments to quality of life.
Time frame: 20 weeks
Sebum excretion
Measure of skin sebum via sebumeter.
Time frame: 12 weeks
Sebum excretion
Measure of skin sebum via sebumeter
Time frame: 20 weeks
Gut microbiome assessment
Gut microbiome shift for short-chain fatty acid producing bacteria via stool sample
Time frame: 12 weeks
Gut microbiome assessment
Gut microbiome shift for short-chain fatty acid producing bacteria via stool sample
Time frame: 20 weeks
Skin microbiome diversity
Shift in the Shannon diversity of the skin microbiome through adhesive strip and swab collection.
Time frame: 12 weeks
Skin microbiome diversity
Shift in the Shannon diversity of the skin microbiome through adhesive strip and swab collection.
Time frame: 20 weeks