Spinal surgery is often burdened by perioperative pain and its treatment presently represents a challenge for anesthetists. An inadequate intra and postoperative analgesic therapy leads to a delay in the mobilization of the patients, prolonged hospital stay and thromboembolic complications, as well as the onset of chronic pain syndromes . Effective pain treatment can help improve surgical outcome for patients undergoing spinal surgery. From the pathophysiological point of view pain in vertebral surgery can originate from different anatomical structures: vertebrae, discs, ligaments, dura mater, facet joints, muscles and skin-subcutis. The terminal innervation of these tissues originate from the dorsal branches of the spinal nerves, and this represents a target a multimodal approach to perioperative analgesia in vertebral surgery. Systemically administered drugs such as NSAIDs, opioids, ketamine, intravenous lidocaine could benefit from the addition of locoregional therapies such as neuraxial blocks (anesthesia peridural or subarachnoid) or as shown more recently by other anesthesia techniques locoregional ultrasound-guided In recent years the anesthesiological interest has focused on the Erector Spinae Plane Block (ESPB). First described by Forero et al, it is a paraspinal interfascial block targeting the dorsal and ventral branches of the spinal nerves just after their emergence from the spinal cord. In the ultrasound-guided technique the local anesthetic is injected between the deep fascia of the muscle itself and the transverse processes of the vertebrae at the level interested. The aim of this study is to evaluate the efficacy of ESPB when compared to wound infiltration in patients undergoing laminectomy
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
112
Bilateral ultrasound guided injection of saline in the erector spinae plane (below erector spinae plane muscle group and above the transverse process of the vertebra)
Blinded injection of saline in the skin, subcutaneous tissue and muscles at the site of surgical incision
Bilateral ultrasound guided injection of local anesthetic (ropivacaine 0.35%, 40ml) in the erector spinae plane (below erector spinae plane muscle group and above the tranverse process of the vertebra)
Blinded injection of local anestetic (ropivacaine 0.35%, 40ml) in the skin, subcutaneous tissue and muscles at the site of surgical incision.
University Hospital of Padova
Padua, Veneto, Italy
RECRUITINGTramadol consumption
Postoperative tramadol consumption
Time frame: Evaluated from extubation for the first post-operative 24 hours
Pain 0 hours
Pain measured with Numeric Rating Scale (0-10)
Time frame: At extubation
Pain 6 hours
Pain measured with Numeric Rating Scale (0-10)
Time frame: 6 hours after end of surgery
Pain 12 hours
Pain measured with Numeric Rating Scale (0-10)
Time frame: 12 hours after end of surgery
Pain 24 hours
Pain measured with Numeric Rating Scale (0-10)
Time frame: 24 hours after end of surgery
Time to first analgesic requirement
Time in minutes to first analgesic requirement
Time frame: 24 hours after end of surgery
Incidence of post operative nausea-vomiting
Incidence of post operative nausea-vomiting
Time frame: 24 hours after end of surgery
Incidence of post operative respiratory depression
Incidence of post operative respiratory depression
Time frame: 24 hours after end of surgery
Incidence of post operative pruritus
Incidence of post operative pruritus
Time frame: 24 hours after end of surgery
Incidence of post operative motor block
Incidence of post operative motor block
Time frame: 24 hours after end of surgery
Intraoperative opioid consumption
Intraoperative difference in consumption of fentanyl.
Time frame: At extubation
Evaluation of patient satisfaction
Evaluation of patient satisfaction of analgesia on a numeric rating score from 0-10.
Time frame: 24 hours after end of surgery
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