Transgender people can benefit from psychological, psychiatric, endocrinological support, sexual reassignment surgery, sexology support and dermatological care. The value of transitional care courses is scientifically recognized. Currently, the modalities of decision and realization of the care paths are heterogeneous on the territory, little standardized, and are the subject of debates between representatives of users and medical teams. The french national report of IGAS from 2011 warns of the need to argue and legitimize care practices through more numerous, more exhaustive scientific studies, presenting a better level of evidence Since 2011, no prospective study has been carried out on the national and international level, making it possible to assess the relevance of the planned care modalities. This research project, conducted over five consecutive years at the first contact of a transgender people with a care device, aims to correlate a variation in the quality of life of people with the characteristics of the care methods provided. This is a first proposal to assess care practices for transgender people. The results of this study would first allow us to infer the care modalities most suited to the needs of people. Secondly, secondary hypotheses could support new experimental protocols.
This research is a prospective multicenter cohort study with a 3-year and 5-year follow-up of transgender people in medical transition. Main aim: Evaluate the evolution of the quality of life during five years in transgender people who benefit from transition support cares. Secondary objectives: Secondary objective n°1 : Identify the different factors that influence the evolution of quality of life evaluated over three years in transgender people who benefit from transition support cares. Secondary objective n°2 : Evaluate the evolution of the satisfaction of the shared medical decision for transgender people in medical transition. Secondary objective n°3 : Evaluate the evolution of the satisfaction of body image for transgender people in medical transition. Secondary objective n°4 : Evaluate the evolution of psychiatric comorbidities for transgender people in medical transition. Secondary objective n°5 : Evaluate the benefits and limits in long term (five years) on the quality of life, the satisfaction of the shared medical decision, the satisfaction of body image and the evolution of psychiatric comorbidities.
Study Type
OBSERVATIONAL
Enrollment
400
Centre Hospitalier de Béziers
Béziers, France
CHU de Bordeaux
Bordeaux, France
CHU de Brest
Brest, France
CHU de Caen
Caen, France
CHU de Lille
Lille, France
Maison de Santé Lille Moulins
Lille, France
Maison de Santé Lille Sud
Lille, France
CHU de Lyon
Lyon, France
G..R.E.T.T.I.S
Lyon, France
Hopital de la Conception - Marseille
Marseille, France
...and 3 more locations
Quality of life scores
Scores on the WHOQOL BREF (World Health Organisation Quality Of Life) scale
Time frame: 3 years
Social factors (age, gender, profession, knowledge of care system)
Answers given by the patient during interview
Time frame: Baseline and 6 months, 12 months, 18 months, 24 months, 30 months, 3 years and 5 years
Satisfaction of the shared medical decision
Scores on the CDIS (Clinical Decision-making Involvement and Satisfaction) clinical decision making involvement and satisfaction score 15 questions scored 1-5 (totally disagree, strongly disagree, neither agree nor disagree, strongly agree, totally agree)
Time frame: 6 months, 12 months, 18 months, 24 months, 30 months, 3 years and 5 years
Satisfaction of body image
Score on the BIS (Body Image Scale), total score ranges from 0 to 30, A higher score means a higher level of body image disturbance
Time frame: 6 months, 12 months, 18 months, 24 months, 30 months, 3 years and 5 years
General psychopathology
French version of Mini International Neuropsychiatric Interview (DSM)
Time frame: 6 months, 12 months, 18 months, 24 months, 30 months, 3 years and 5 years
Anxiety and depression
Anxiety and depression scores on the HAD scale (Hospital Anxiety and Depression scale), a score upper 8 means is considered as a risk of an anxiety or depressive disorder
Time frame: 6 months, 12 months, 18 months, 24 months, 30 months, 3 years and 5 years
Quality of life scores
Scores on the WHOQOL BREF (World Health Organisation Quality Of Life) scale
Time frame: 6 months, 12 months, 18 months, 24 months, 30 months, 5 years
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