Effect of Nutritional Supplements on Clinical Outcomes in Patients With Prediabetes and Obesity

Inclusion Criteria: * According to the American Diabetes Society (ADA) 2010 standard: meet one of the following (1) fasting blood glucose at 100 mg/dl to 125 mg/dl; (2) sugar load 2h blood glucose at 140 mg/dl to 199 mg/dl; (3) glycosylated hemoglobin in 5.7% to 6.4% * Body mass index (BMI) ≥ 25 and ≤ 35kg/m2 * Have lived locally for at least half a year and have a fixed residence * No other clinical trials were participated in in the 3 months prior to the trial * Mental health, being able to take care of oneself in life Exclusion Criteria: * People with confirmed diabetes * Weight change of more than 10% over the past 3 months * Pregnant or lactating women, men and women planning to become pregnant within two years, or unwilling and unable to use contraception during the study period (women only) * People who are allergic to the ingredients of nutritional supplements * Those who have lost weight by any medication (including appetite suppressants such as fluprophenylpropanine, progesterone, laxatives, etc., and diet pills with various Traditional Chinese medicine ingredients) or surgery in the past 3 months * Patients who have received medical treatment for the following diseases in the past 3 months: diabetes, cholecystitis, peptic ulcer, inflammatory bowel disease, acute urinary tract infection, hyperthyroidism, etc., or patients with chronic gastrointestinal diseases with symptoms of nausea, vomiting and diarrhea in the past month * Suffer from severe organic diseases such as cancer, coronary heart disease, myocardial infarction and stroke * Presence of pituitary-adrenal axis dysfunction; secondary obesity due to other diseases (e.g., Cushing syndrome, hypothyroidism, etc.)