The Immune Response to Stroke

University of Oslo40 enrolled

Overview

Some patients develop cognitive decline after a stroke, but we don't always understand the mechanisms. It has been proposed that a proportion of the patients develop an autoimmune immune response, and that this could potentially explain the cognitive decline in some of the patients. The current study aims to investigate this hypothesis in a subgroup of patients with stroke.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Stroke, Acute Dementia

Interventions

Analysis of post-stroke immune responsesOTHER

Analysis of immune responses in peripheral blood

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Stroke \< 72 h * Age \> 18 years Exclusion Criteria: * Brain hemorrhage verified by CT or MRI scan * Previous or present immunological disease or other serious comorbidity * Ongoing immune respons after infection or vaccination \< 1 month * Cognitive without ability to understand and/or give an informed consent to participate in the study

Locations (1)

Akershus University Hospital

Lørenskog, Norway

RECRUITING

Outcomes

Primary Outcomes

The B cell and T cell response in peripheral blood

Time frame: 1 day (subject inclusion)

Central Contacts

Andreas Lossius, MD, PhD

CONTACT

+47 930 68 515 postmottak@medisin.uio.no

Data from ClinicalTrials.gov

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