Dexmedetomidine Versus Hyalase Treatment of Carpal Tunnel Syndrome

Assiut University60 enrolled

Overview

Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy, this study aims to investigate if, and to what extent hydro-dissection hyalase and saline versus dexmedetomidine upon the median nerve could offer symptoms and clinical improvement

Carpal tunnel syndrome (CTS) is the most common compression syndrome the upper extremities. Its problem has a high prevalence ranged estimated prevalence of 3.8% in the general population, 3 and 7.8% in the working population. It occurs at any age, especially in individuals in their 40s to 60s, and the male: female ratio is reported to be 3:7. A lot of treatment modalities have been tried to improve the condition, starting from local anesthetic injection, steroid, and up to surgical decompression of the nerves.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Carpal Tunnel Syndrome Pain, Chronic

Interventions

DexmedetomidineDRUG

injection of 1 microgram/kg dexmeditomidine + 10 cc saline injection nearby median nerve as hydrodissection

HyalaseDRUG

injection of Hyalase + 10 cc saline injection nearby median nerve as hydro-dissection

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * adult patients * complaining of carpal tunnel syndrome of 3 month duration or more * diagnosed axonal neuropathy using electrodiagnosis , nerve conduction study Exclusion Criteria: * • patient refusal infection at the site of intervention * local anesthetic allergy

Locations (1)

Emad Zarief Kamel Said

Asyut, Egypt

Outcomes

Primary Outcomes

Pain alleviation

pain alleviation improvement of pain measured by visual analog scale , no pain the scale equal zero , and worst pain the scale equal 10

Time frame: 6 months

Secondary Outcomes

Median nerve cross sectional area

Changes in ultrasound imaging change of cross sectional area in cubic mellimeter

Time frame: 6 months

Data from ClinicalTrials.gov

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