Intraperitoneal Instillation of Levobupivacaine With Morphine Versus Levobupivacaine With Magnesium Sulfate for Postoperative Analgesia

Sohag University60 enrolled

Overview

This is a prospective randomized study that included 60 patients and was divided into two equal groups of patients who were scheduled for LC, Ages 18 and 60 years, both sexes, ASA I-II and BMI 19 - 39. Group A received 30 ml levobupivacaine (0.25%) plus 3 mg morphine intraperitoneal at the site of surgery in the bed of the gallbladder via the navel port with the patient in a Trendelenburg position, Group B received 30 ml levobupivacaine (0.25%) plus 50 mg/kg magnesium sulfate in the same pattern as in the A group.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Post Operative Pain

Interventions

intraperitoneal levobupivacaine and morphine

istillation of the peritoneum with levobupivacaine mixture with morphine

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who were scheduled for L.C, * Ages 18 and 60 years * ASA I-II and * BMI 19 - 39 Exclusion Criteria: * Patients with hepatic or renal dysfunction * use of opioids 24 hrs prior to the study * treatment with steroids prior to surgery * drug or alcohol abuse, allergy to any of the study drugs * chronic pain syndrome as a result of neurological disease

Locations (1)

‪Khalid abdelal‬

Sohag, Egypt

Outcomes

Primary Outcomes

reduction of postoperative pain

reduction of post operative visual analogue score

Time frame: 8 hours

Data from ClinicalTrials.gov

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