Current recommendations consider surgical ligation and supra-selective embolization as equivalent in terms of efficacy and there is no clear consensus to choose between one and the other technique. In the absence of medico-economic studies, these recommendations could not be based on any differences in efficiency between the two techniques. The management of patients with severe non-traumatic epistaxis remains controversial and varies according to the hospital and/or university centers. In practice, the use of one or the other technique depends on the habits of each reference center.
The hypothesis is that early ligation of the sphenopalatine arteries would reduce the costs of care for the community while improving the quality of life of patients compared to supra-elective embolization. This medico-economic superiority could go through: * reduction in the number of recurrences * reduction in the length of hospital stays. * reduction in the cost of postoperative care. * reduction of iatrogenic complications * improvement of functional suites upon return home. * Tertiary prevention of dependency, particularly among the elderly
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
180
the surgical ligation of one or both sphenopalatine arteries by endoscopic way.
occlusion of the terminal branches of the nasal external carotid artery.
University Hospital
Toulouse, France
RECRUITINGincremental cost-utility ratio
the cost-utility ratio integrating direct medical and non-medical costs
Time frame: Month 18
number of recurrences
Time frame: Month 18
time to first recurrence
Time frame: Month 18
the number of complications
Time frame: Month 18
nature of complications
Time frame: Month 18
quality of life with EQ-5D-5L
Time frame: Month 18
quality of life with SNOT 22
Time frame: Month 18
the number of hospitalizations
Time frame: Month 18
duration of hospitalizations
Time frame: Month 18
the addiction with KATZ scale
Time frame: Month 18
incremental cost-effectiveness ratio
the incremental cost-effectiveness ratio (cost/number of recurrences avoided) from the perspective of the community
Time frame: Month 18
the description of the costs of care
only for non-randomized patients
Time frame: Month 18
financial benefit (1 year)
the annual financial benefit of routine implementation of arterial ligation in the treatment of severe epistaxis, from a community perspective
Time frame: Month 12
financial benefit (5 year)
the 5-year financial benefit of routine implementation of arterial ligation in the treatment of severe epistaxis, from a community perspective
Time frame: Year 5
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