A Study to compare pharmacokinetics, pharmacodynamics and safety of UI058 and UIC202004 in healthy subjects
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
41
UI058 1Tab/day for 7days
UIC202004 1Tab/day for 7days
Chungbuk national university hospital
Cheongju-si, North Chungcheong, South Korea
AUCtau,ss(Area under the plasma drug concentration-time curve within a dosing interval at steady state
evaluation PK for Rabeprazole after multiple dose
Time frame: Day 7, 0~24hours
percent change from baseline in integrated gastric acidity for 24-hour interval after 7th dose
evaluation PD for ambulatory 24hour pH monitor
Time frame: baseline versus multiple dose during 7days
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