The objective of this study is to evaluate the IOP-lowering effect when subjects are switched from various latanoprost-based regimens to Rocklatan. Subjects will stop their IOP-lowering medical therapy regimen and dose with Rocklatan for the duration of the study (12 weeks).
Enrollment will be stratified according to subject's IOP-lowering medical therapy regimen as follows: * Latanoprost monotherapy (Latanoprost Mono) * Latanoprost plus 1 additional IOP-lowering agent (Latanoprost +1) * Latanoprost plus 2 additional IOP-lowering agents (Latanoprost +2) Aerie Pharmaceuticals was acquired by Alcon Research LLC on November 22, 2022.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
136
Commercially available ophthalmic solution indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension
North Valley Eye Medical Group
Mission Hills, California, United States
Mean Percent Change From Baseline in Intraocular Pressure (IOP) at Week 12
IOP was measured using Goldmann applanation tonometry at the Baseline and Week 12 visits. One eye (study eye) contributed data to this analysis. A negative value indicates an improvement in IOP. No hypothesis testing was prespecified for this endpoint.
Time frame: Baseline (Day 0 pretreatment), Week 12
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