Evaluation of MCM5 in Postmenopausal Bleeding Patients

Inclusion Criteria: * Patients 18 years of age or older * Patients who are at least 1 year post-menopausal i.e. have not had a menstrual period for at least one year * Patients who, in the opinion of the Investigator, are suitable for standard gynaecological investigations as part of normal clinical practice * Patients who are, in the opinion of the Investigator, able to understand the purpose of the study and provide a full void urine specimen * Patients who are able to give voluntary, written informed consent to participate in this study and from whom consent has been obtained Exclusion Criteria: * Patients with known symptomatic calculi within the urino-genitary system * Patients currently undergoing chemotherapy or radiotherapy * Patients who have previously been diagnosed with bladder or renal cancer who are currently in follow up * Patients with a medical contraindication to endometrial biopsy * Patients who do not wish to have an endometrial biopsy even if deemed necessary by the treating physician * Patients who have had urological instrumentation to the urinary tract within 14 days prior to the test (including catheterisation) * Patients who have had any gynaecological instrumentation in the previous 14 days