evaluate the interest of proton pump inhibitors in subjects with or with GI symptoms who intend to observe fasting in Ramadan. The investigators will compare the effectiveness of proton pump inhibitors to prevent or reduce the signs of dyspepsia during Ramadan compared to placebo.
evaluate the interest of proton pump inhibitors in subjects with or with GI symptoms who intend to observe fasting in Ramadan. Investigators will compare the effectiveness of proton pump inhibitors to prevent or reduce the signs of dyspepsia during at least Ramadan compared to placebo. The study will be conducted at least from April 2019 to at least June 2030.The study is prospective, two parallel groups, randomized controlled and double blind.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
500
Patients are given a box of capsules of which they take 1capsule/day during the month of ramadan
Patients are given a box of capsules of which they take 1capsule/day during the month of ramadan
Emergency department of university hospital Fattouma Bourguiba of Monastir Monastir, Monastir Tunisia
Monastir, Tunisia
Overall symptom relief during the 4 weeks of treatment
Relief of dyspepsia symptoms during the treatment period according to the decrease of SF-LDQ score
Time frame: 30 days after inclusion
number of days without dyspepsia
the number of days with SF-LDQ score \<1
Time frame: 30 days after inclusion
quality of life assessment
quality of life assessment ccording to the SF-36 score
Time frame: 30 days after inclusion
Patients satisfaction of the treatment
Patients satisfaction according to Likert score
Time frame: 30 days after inclusion
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