Since the beginning of COVID-19 pandemic situation, several modes of ventilation have been tried to correct the hypoxaemia induced by SARS-CoV-2 virus. A few recent studies have concluded that high-flow nasal oxygen therapy (OptiFlow™) is beneficial in COVID-19. All mainly conclude that the use of OptiFlow™ avoid intubations and decrease hospitalization duration in critical care services. At the emergency medical service 83 (SAMU 83), it has been decided to extend this ventilation mode during patient secondary transfers (transfer from an intensive care unit/other hospital unit/emergency department to another hospital's intensive care unit). The emergency medical service 83 has equipped its intensive-care ambulances with OptiFlow™ in order not to interrupt this ventilation mode during transport. The hypothesis is that patients with a severe respiratory form of COVID-19 transported from one health facility to another by the emergency medical service 83 on high-flow nasal oxygen therapy has a reduced risk of intubation compared to the other modes of non-invasive ventilation (NIV) and High Concentration oxygen Masks (HCM).
Retrospective observational study in France including COVID-19 infected patients taken care of by the emergency medical service 83 (SAMU 83) for a secondary transport between1st March 2020 and 31th December 2021.
Study Type
OBSERVATIONAL
Enrollment
229
Use of high flow nasal oxygen therapy during secondary transport by emergency medical service 83 (SAMU 83).
Use of other non-invasive ventilation or high concentration oxygen masks during secondary transport by emergency medical service 83 (SAMU 83).
Centre Hopitalier Intercommunal Toulon - La Seyne sur Mer
Toulon, Var, France
Intubation rate
Rate of intubation during the first 24 hours after arrival in the destination Intensive Care Unit (ICU)
Time frame: 24 hours
Mortality rate
Rate of patients alive at Day 28.
Time frame: 28 days
ICU length of stay
Number of days spent in intensive care unit of destination
Time frame: At the moment of Intensive care unit discharge, up to 1 month
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