Remote Ischemic Conditioning for the Treatment of Stroke-related Insomnia

Inclusion Criteria: * Aged 18 to 70 years old; * mRS≤3; * Meeting the DSM-IV diagnostic criteria for insomnia: in the past one month, the presence of any of the following symptoms: a. have difficulty falling asleep (sleep latency \>30 minutes); b. have trouble in maintaining sleep; c. early awakening, accompanied by impaired daytime function, with symptoms occurring more than three times a week, lasting at least 2 weeks; * Written informed consent provided by the patients or their legal relatives. Exclusion Criteria: * Chronic insomnia (PSQI≥8) or other sleep disorders was diagnosed 3 months before onset of stroke; * Presence or past history of neuropsychiatric diseases such as epilepsy, brain tumors, neurodegenerative disorders, restless leg syndrome, periodic leg movement; * Schizophrenia, significant anxiety and depression (HAMA≥14 points, HAMD≥17 points) with moderate to high suicide risk, etc; * Serious infection, malignancy, and other serious medical conditions (acute heart, liver, renal failure and other diseases); * Have taken any medications (antipsychotics, hypnotics, antidepressants, etc.) that interfere with sleep in the latest two weeks; * Have work shift or jet lag experience 4 months before enrollment Infants, Pregnant or lactating women.