Intracranial Stimulation Mapping In Epilepsy

University of Minnesota30 enrolled

Overview

This is a single group prospective study to determine the feasibility for generating brain maps that localize cerebral functions and inter-regional information flow in partial epilepsy in adult patients.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Epilepsy

Interventions

Functional mappingOTHER

Intracranial EEG data acquisition, observation and behavioral testing, and intracranial electrical stimulation

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Male or female 18 years and older at screening. * Written informed consent is obtained from the participant to comply with the requirements of the study. * Stated willingness to comply with all study procedures and availability for the duration of the study * Currently undergoing clinically indicated intracranial EEG monitoring for planning of epilepsy surgery in the University of Minnesota/MINCEP program. Exclusion Criteria: * Pregnancy ruled out prior to approval for intracranial EG monitoring. * Persons who are rendered temporarily or permanently invulnerable by inability to understand the research due to study complexity, cognitive impairment, or by inability to make independent decisions owing to University of Minnesota or to Fairview health services.

Locations (1)

University of Minnesota

Minneapolis, Minnesota, United States

RECRUITING

Outcomes

Primary Outcomes

The effect of prefrontal direct electrical brain stimulation on cognitive effort

The change in subjective value of cognitive effort (area under the curve) after direct electrical brain stimulation to different areas of the prefrontal cortex during an effortful task

Time frame: Immediately after stimulation sessions

Central Contacts

Matthew Maple

CONTACT

612-946-1424 maple036@umn.edu

Data from ClinicalTrials.gov

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