An open label pilot study in mild to moderate AD patients to assess the effects of treatment with ECHS AD pulsed electromagnetic treatment device on disease progression. Enrolled patients will receive active devices. They will treat themselves at home three times a day for 15 minutes over 120 days. Primary end points are the The Alzheimer's Disease Assessment Scale-Cognitive Subscale and the Mini-Mental State Exam. Participants will be followed-up for 9 months post-treatment.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
40
Pulsed electromagnetic therapy device
Hackensack Medical Center
Hackensack, New Jersey, United States
RECRUITINGThe Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog)
Assessment consisting of 11 tasks, taking up to 30mins, to measure the severity of cognitive dementia symptoms. Score 0-70, Higher number, more severity.
Time frame: Change between day 0, and 30, 60, 90, 120, 150, 240, 310, 400 days
Mini-Mental Status Exam (MMSE)
Clinician assessment of cognitive impairment. Scoring 0-30, lower score, more severity
Time frame: Change between day 0, and 30, 60, 90, 120, 150, 240, 310, 400 days
Global Deterioration questionnaire
Clinician assessment of cognitive impairment. Scored 0-7, higher score, greater severity
Time frame: Change between day 0, and 30, 60, 90, 120, 150, 240, 310, 400 days
Quality of Life Scale
Clinician assessment of cognitive impairment. Scored 0-7, higher score, greater severity
Time frame: Change between day 0, and 30, 60, 90, 120, 150, 240, 310, 400 days
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