Age and Refraction in Predicting Myopia Progression in COVID-19

Tianjin Eye Hospital34,400 enrolled

Overview

To determine the longitudinal changes of age and refraction in predicting myopia progression with risk under the coronavirus disease 2019 (COVID-19) pandemic in a 3-year follow-up of a Chinese cohort.

This was part of the large-scale Tianjin Eye Study, a population-based cohort study that longitudinally investigates the relationship between the age, refraction, and development of childhood RE in Tianjin, China.

Study Type

OBSERVATIONAL

Enrollment

34,400

Conditions

Refraction Error Myopia

Interventions

screeningOTHER

This study included 34,400 students, as part of the Tianjin Eye Study who performed a 3-year follow-up from 2019 to 2021. All participants underwent yearly noncycloplegic refraction and ocular examinations. Time-related changes in sphere, cylinder, and spherical equivalent (SE) measurements in both sexes were analyzed.

Eligibility

Sex: ALLMin age: 6 YearsMax age: 15 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * no concurrent eye disease; * age 6-15 years. Exclusion Criteria: * significant systemic illnesses * ocular conditions that could affect the corneal curvature, including congenital corneal diseases, * pterygium, keratoconus, other corneal degeneration or dystrophy conditions, * media opacity, uveitis, glaucoma * a history of intraocular surgery, refractive surgery, * neurologic or retinal diseases, current corneal refractive therapy (ortho-K), * low-dose atropine therapy for myopia control

Locations (1)

Tianjin Eye Hospital

Tianjin, China

Outcomes

Primary Outcomes

changes of sphere

Time frame: change from baseline at 36 months

changes of cylinder

Time frame: change from baseline at 36 months

changes of spherical equivalent

Time frame: change from baseline at 36 months

changes and distribution of visual acuity

Time frame: change from baseline at 36 months

Data from ClinicalTrials.gov

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