The purpose of this project is to investigate the effects of breaking up prolonged sitting on postprandial metabolic responses, gut hormones secretion and energy balance in sedentary overweight and obese adults.
Two trials are included in this project - Prolonged sitting and Breaking sitting. In the Prolonged sitting trial, after consuming breakfast, participants sat on a chair for 180 min. After 180 min, lunch was provided. After finishing lunch, participants sat on a chair for another 120 min. In the Breaking sitting trial, after consuming breakfast, participants walked 2 min on a treadmill every 20 minutes for the following 180 min. For the remainder of the time participants sat on the chair. After 180 min, lunch was provided. After finishing lunch, participants continued 2 min of walking every 20 min for the following 120 min. Blood samples were collected in a regular pattern throughout the trials. Energy balance (e.g., energy intake and spontaneous physical activity) was assessed using food diary and an accelerometer until midnight in the trial days once participants left laboratory.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
13
After consuming breakfast, participants sat on a chair for 180 min. After 180 min, lunch was provided. After finishing lunch, participants sat on a chair for another 120 min.
After consuming breakfast, participants walked 2 min on a treadmill every 20 minutes for the following 180 min. For the remainder of the time participants sat on the chair. After 180 min, lunch was provided. After finishing lunch, participants continued 2 min of walking every 20 min for the following 120 min.
National Taiwan Normal University
Taipei, Taiwan
Gut hormones responses
Changes in blood gut hormones responses (e.g., GLP-1, PYY and GIP concentrations measured in pmol/L) between trials
Time frame: 320 minutes
Visual analogue scale (VAS)
Changes in VAS from 0-100 mm (e.g., appetite and mood, etc.) between trials
Time frame: 320 minutes
Energy intake
Changes in energy intake (e.g, using a food diary to record) after leaving the laboratory until midnight
Time frame: 600 minutes after leaving the labalotory
Physical activity level
Changes in physical activity level (e.g., using an accelerometer to record) after leaving the laboratory until midnight
Time frame: 600 minutes after leaving the labalotory
Lipid profile
Changes in blood lipid profile (e.g., TAG and cholesterol, etc.) between trials
Time frame: 320 minutes
Blood pressure
Changes in blood pressure (e.g., diastolic and systolic blood pressure) between trials
Time frame: 320 minutes
Computerized cognitive testing
Changes in cognitive function (e.g., accuracy and reaction time) between trials
Time frame: 320 minutes
Incremental area under curve (iAUC) for metabolic health
Changes in incremental area under curve (iAUC) for insulin and glucose between trials
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: 320 minutes