Salivary Melatonin Levels and Sleep Quality in Patients With Burning Mouth Syndrome

University of Zagreb45 enrolled

Overview

Burning mouth syndrome is an idiopathic condition characterized by symptoms burning and / or pain of the oral mucosa with an orderly clinical finding. So far not found a unique way of treatment. It is a diagnosis that impairs the quality of life of patients, and consequently it can affect the quality of sleep. Melatonin is a hormone secreted from pineal gland and regulates the day-night rhythm of man, and whose production in the body decreases aging. The level of melatonin in saliva correlates well with the level of melatonin in plasma, therefore they are advantages of determining from saliva painlessness and non-invasiveness of the procedure itself. The purpose of this study was to compare the level of melatonin in saliva and the quality of sleep with help of the Epworth Sleepiness Scale in patients with burning mouth syndrome and control groups of patients without subjective oral disorders and with an orderly clinical finding.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Burning Mouth Syndrome Melatonin

Interventions

Epworth's sleepiness scale; unstimulated saliva sample

Outcomes

Primary Outcomes

determining the level of salivary melatonin

The level of salivary melatonin will be determined in frozen samples of unstimulated saliva samples

Time frame: January 2021-July 2021

Secondary Outcomes

determining the difference in Epworth's sleepiness scale

The test is a list of eight situations in which you rate your tendency to become sleepy on a scale of 0, no chance of dozing, to 3, high chance of dozing. Total score is graded from 0-24. 0-7:It is unlikely that you are abnormally sleepy. 8-9:You have an average amount of daytime sleepiness. 10-15:You may be excessively sleepy depending on the situation. You may want to consider seeking medical attention. 16-24:You are excessively sleepy and should consider seeking medical attention.