One of the main repercussions of POI is infertility. When the diagnosis of POI is announced, the question of fertility is addressed and the patient is often directed towards egg donation or adoption when she has a parental project. However, there are cases of spontaneous pregnancies after diagnosis. This study was conducted to determine the proportion of patients with POI who were able to realize a parental project after diagnosis in the long term and by what means.
The investigators propose to study patients with POI who were hospitalized in the endocrinology and reproductive medicine department of the Pitié-Salpêtrière Hospital for the etiological assessment of ovarian failure and its consequences between December 31, 1982 and January 12, 2021. The investigators will only include patients who were admitted to the day hospital because we have a complete etiological workup and a complete history for them, which allows investigators to describe the population properly. The patients must be over 18 years old at the time of the survey in order to be able to evaluate the presence of a parental project only in adult patients. Patients for whom there is no valid contact information in the computer file (postal address or valid email address or cell phone number) or whose last consultation was more than 2 years ago will be excluded. Patients with Turner syndrome will be excluded because they may have comorbidities, particularly cardiac, that contraindicate pregnancy. Patients with POI secondary to oncological treatments (gonadotoxic chemotherapy or pelvic radiotherapy) will also be excluded because of the uncertain prognosis and the contraindications to pregnancy in case of hormone-dependent tumors.
Study Type
OBSERVATIONAL
Enrollment
324
Survey on the parental project and its realisation
Service d'endocrinologie et médecine de la reproduction
Paris, France
Realisation of parental project
Determine proportion of patient who realised a parental project after the diagnosis of POI
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed
Determine how and to what extent they have carried out their parental project
Evaluation if, after the diagnosis of POI, the parental project was realized through: spontaneous pregnancy or egg donation, simple stimulation or in vitro fertilization, embryo reception, or the adoption of a child after the diagnosis of POI
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed
determine how many children on average these patients had after the diagnosis of POI.
Evaluation of the number of children born after the diagnosis of POI
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed
determine the delay between the diagnosis of POI and the birth of the first child after the diagnosis according to the method
Evaluation of the time between the diagnosis of POI and the birth of the first child after diagnosis according to the method (egg donation, spontaneous pregnancy, adoption, etc.)
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed
Survey. Describe the characteristics of patients who were able to have a child after diagnosis
Evaluation of the characteristics of patients who were able to have a child after diagnosis: o age at diagnosis
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed
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Survey. Describe the characteristics of patients who were able to have a child after diagnosis
Evaluation of the characteristics of patients who were able to have a child after diagnosis: o AMH level
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed
Survey. Describe the characteristics of patients who were able to have a child after diagnosis
Evaluation of the characteristics of patients who were able to have a child after diagnosis: o FSH level
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed
Survey. Describe the characteristics of patients who were able to have a child after diagnosis
Evaluation of the characteristics of patients who were able to have a child after diagnosis: o presence of follicles on ultrasound
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed
Survey. Describe the characteristics of patients who were able to have a child after diagnosis
Evaluation of the characteristics of patients who were able to have a child after diagnosis: o cause of POI
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed
Survey. Describe the characteristics of patients who were able to have a child after diagnosis
Evaluation of the characteristics of patients who were able to have a child after diagnosis: o number of pregnancies prior to diagnosis
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed
Survey. Describe the characteristics of patients who were able to have a child after diagnosis
Evaluation of the characteristics of patients who were able to have a child after diagnosis: o number of children before diagnosis
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed
Survey. Describe the characteristics of patients who were able to have a child after diagnosis
Evaluation of the characteristics of patients who were able to have a child after diagnosis: o normal puberty
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed
Survey. Describe the characteristics of patients who were able to have a child after diagnosis
Evaluation of the characteristics of patients who were able to have a child after diagnosis: o age at menarche
Time frame: data from patients with a diagnosis between 31/12/1982 and 12/01/2021 and whose opposition to the study is not expressed