To investigate the effect of MTX discontinuation for 1 week on vaccination response to Covid-19 booster vaccination in RA patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
40
MTX continuation
Seoul National University Hospital
Seoul, South Korea
RECRUITINGCovid-19 antibody titer before and after Covid-19 vacciation
Titer and geometric mean titers (GMTs) of neurolizing antibody after vaccination
Time frame: 2 weeks
T cell activation after vaccination
Percentage of activated T cells after vaccination
Time frame: 2, 4, 16 weeks
B cell activation after vaccination
Percentage of activated b cells after vaccination
Time frame: 2, 4, 16 weeks
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