This is a comparative, open label, parallel group, non interventional study aims to assess the effect of Ectoine containing eye drops on stromal haze, pain and epithelial healing after Photorefractive keratectomy (PRK). The patient apply Ectohylo eye drops (Ectoine +Sodium Hyauronate) in the right eye and Polyfresh Extra eye drops (Carboxymethyl cellulose + Sodium Hyauronate ) in the left eye plus the routine post PRK treatment in both eyes. Post operative pain , epithelial healing and corneal densitometry is observed in both eyes.
Photorefractive keratectomy (PRK) is a commonly used operation for laser vision correction. The main fears of this type of laser vision correction is corneal haze, delayed epithelial healing and postoperative severe pain. Ectoine is a natural compound that has the ability to protect biological membranes from damage and environmental effects. This study assess the use of Ectoine containing eye drops to protect the bare ocular surface and reduce inflammation after PRK that will inturn is expected to affect the post operative corneal haze, pain, and epithelial healing .
Study Type
OBSERVATIONAL
Enrollment
15
using Ectohylo eye drops post operative after PRK in the right eyes of the patients
Tanta University
Tanta, El Gharbia, Egypt
RECRUITINGCorneal Densitometry (assesed by Pentacam).
Post photo refractive keratectomy early haze (3 months after operation) assesed by Pentacam densitometry
Time frame: 3 months post operative
Pain score (0 -10)
pain in the first 2 days post operative (graded 0 to 10)
Time frame: 2 days
Time of Epithelial healing (days)
Time required for epithelial healing after PRK in days
Time frame: 2-7 days
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