There are currently only few data on the coronary artery calcium score in patient with diabetes in France, and the diagnostic and therapeutic attitudes towards a high coronary artery calcium score are not standardized and depend on clinical practices, which may vary from one center to another. The proposed multicenter prospective study would provide a better understanding of the epidemiological particularities of the coronary artery calcium score in French diabetics, refine the indications for better performance of the examination, and compare attitudes when this score is high.
The prevalence of coronary heart disease in patient with diabetes varies according to the patient's age, the duration of the diabetes, the coexistence of other heart disease risk factors, but also the type of diagnostic used to detect it. In addition, clinical symptoms are often lacking in diabetic patients. The latest recommendations from the European Society of Cardiology in 2018 propose a graduation of cardiovascular risk into 3 categories according to the presence of cardiovascular disease, other target organ damage, the duration of diabetes and the coexistence of other heart disease risk factors. The use of imaging can be considered to refine the cardiovascular risk stratification , such as detection of carotid plaque (class IIa), coronary artery calcium score (class IIb) or even the coronary scanner or ischemia tests (class IIb ). In a much more pragmatic and operational way, the French Society of Cardiology and the Francophone Society of Diabetology very recently published a consensus document, proposing a cardiovascular risk stratification based on clinical elements, the existence of other cardiovascular risk factors and target organ damage risk factors, and the use of the coronary artery calcium score to stratify in particular patients qualified as high risk.
Study Type
OBSERVATIONAL
The evaluation of the coronary artery calcium score will be performed with chest CT scan
CHU de Bordeaux
Bordeaux, France
CHU de Limoges
Limoges, France
CHU de Nice
Nice, France
Hôpital Lariboisière, APHP
Paris, France
Proportions of diabetic patients with high coronary artery calcium score
Number of patient with diabetes having a coronary artery calcium score higher than 400
Time frame: day 1
Proportion of patients having a coronary exploration
Number of patient with high coronary artery calcium (\>400) score having a coronary exploration compared with patient with low coronary artery calcium score (\<400)
Time frame: 6 months
Proportion of patients having a myocardial revascularization
Number of patient with high coronary artery calcium score (\>400) having a myocardial revascularization compared with patient with low coronary artery calcium score (\<400)
Time frame: 3 months
Description of adverse events regarding to the coronary artery calcium score
Calculation of number and type of cardiovascular adverse event within patient with high coronary artery calcium score (\>400) or low coronary artery calcium score (\<400)
Time frame: 6 months / 12 months / 18 months / 24 months / 30 months / 36 months / 42 months / 48 months
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Hopital Saint Antoine
Paris, France
CHU de Poitiers
Poitiers, France
CHU de la Réunion
Saint-Denis, France
Centre de Cardiologie de Thionville
Thionville, France
CHU de Tours
Tours, France