As part of the preparation at the Paris 2024 Olympic Games, the French rowing and cycling federations and a consortium of researchers met to reach an ultimate goal: to increase the number of medals in these two disciplines for Paris 2024 Olympics.
The objective of this study is to evaluate the maximum capacity of power production of athletes by describing their power-endurance profile and the physiological factors underlying this maximum power generation capacity. These assessments will guide coaches and athletes for: 1. the best use of athletes' physical abilities (for race strategy, cycling gear ratio or rowing levers) 2. adaptation of training program to improve the maximum capacity of power production of the athletes, in order to increase the number of medals at the Paris Olympics 2024.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
19
Subjects will be subjected to mild hypoxia simulating an altitude of 1750 m (normobaric hypoxia). Hypoxia decreases oxygen supply to tissue and limit exercise capacity. For this, the subjects will inhale a gas mixture depleted in oxygen (enriched in nitrogen). The barometric pressure at 1500 m being 621 mmHg, PIO2 at this altitude (PIO2 = (621 - 47) x 21%) is 120.5 mmHg. For sea level altitude where the barometric pressure is 760 mmHg, the hypoxic gas mixture should contain (x = 120.5 / (760 - 47)) 16.8% O2. Thus, by inhaling a gas mixture that is oxygen-depleted from 21 to 16.8%, subjects (will simulate the altitude of 1750 and) will experience the equivalent of a 20% reduction in oxygen supply.
CEPART
Le Bourget-du-Lac, France
Chu Nantes
Nantes, France
Chu Saint-Etienne
Saint-Etienne, France
Maximum force produced at zero speed in a fatigue-free condition
F0i measurement
Time frame: Month : 3
Speed in a fatigue-free condition
V0i measurement
Time frame: Month : 3
Maximum force produced at zero speed at the end of the 3 min.
F0e measurement
Time frame: Month : 3
Speed up produced at the end of the 3 min.
V0e measurement
Time frame: Month : 3
Maximal oxygen uptake (VO2max)
Cardiac stress test
Time frame: At inclusion
Maximal Ventilation (VEmax)
Cardiac stress test
Time frame: At inclusion
Cardiac output (QCmax)
Cardiac stress test
Time frame: At inclusion
Maximal cardiac frequency (fcmax)
Cardiac stress test
Time frame: At inclusion
Fibre type determination
Muscle biopsy of the vastus lateralis
Time frame: Month : 2
Microvasculature analysis
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Muscle biopsy of the vastus lateralis
Time frame: Month : 2
Muscle enzyme activity (Phosphofructokinase (PFK), lactate dehydrogenase (LDH), citrate synthase (CS) et cyclo-oxygenase (COx))
Muscle biopsy of the vastus lateralis
Time frame: Month : 2
Maximal voluntary force (N)
Comparison before and after exercise
Time frame: Month : 9
Rate of force development
Comparison of force development
Time frame: Month : 9
Evoked forces (N)
Ratio of evoked force at low and high frequencies
Time frame: Month : 9
Maximum force produced at zero speed in a fatigue-free condition after bicarbonate ingestion
F0i measurement
Time frame: Month : 3
Speed in a fatigue-free condition after bicarbonate ingestion
V0i measurement
Time frame: Month : 3
Maximum force produced at zero speed at the end of the 3 min after bicarbonate ingestion
F0e measurement
Time frame: Month : 3
Speed up produced at the end of the 3 min after bicarbonate ingestion
V0i measurement
Time frame: Month : 3
Maximal oxygen uptake (VO2max) after bicarbonate ingestion
Cardiac stress test
Time frame: At inclusion
Maximal Ventilation (VEmax) after bicarbonate ingestion
Cardiac stress test
Time frame: At inclusion
Cardiac output (QCmax) after bicarbonate ingestion
Cardiac stress test
Time frame: At inclusion
Maximal cardiac frequency (fcmax) after bicarbonate ingestion
Cardiac stress test
Time frame: At inclusion
Fibre type determination after bicarbonate ingestion
Muscle biopsy of the vastus lateralis
Time frame: Month : 2
Microvasculature analysis after bicarbonate ingestion
Muscle biopsy of the vastus lateralis
Time frame: Month : 2
Muscle enzyme activity (Phosphofructokinase (PFK), lactate dehydrogenase (LDH), citrate synthase (CS) et cyclo-oxygenase (COx)) after bicarbonate ingestion
Muscle biopsy of the vastus lateralis
Time frame: Month : 2
Maximal voluntary force (N) after bicarbonate ingestion
Comparison before and after exercise
Time frame: Month : 9
Rate of force development after bicarbonate ingestion
Comparison of force development
Time frame: Month : 9
Evoked forces (N) after bicarbonate ingestion
Ratio of evoked force at low and high frequencies
Time frame: Month : 9