Cytomegalovirus Infection After HSCT and PT-CY as GVHD Prophylaxis >> GVHD PROPHYLAXIS ERA

Inclusion Criteria: 1. Age \> 18 years. 2. Period of HSCT: January 1st 2013 to December 31th 2018. 3. GvHD prophylaxis: Post-transplantation Cyclophosphamide (50 mg/Kg on days +3 and +4 or +3 and +5) and calcineurine inhibitors as GvHD prophylaxis. 4. Conditioning chemotherapy regimen and source of stem cells: myeloablative or reduced intensity TBF (Thiotepa 5 mg/Kg D -7-6, Fludarabine 50 mg/m2 D -5-4-3, Busulfan 3,2 mg/Kg D -4-3-2) starting on D-7 followed by peripheral blood or bone marrow infusion on day 0. Exclusion Criteria: 1. Cord blood HSCT. 2. Antilymphocytic or anti thymocytic thymoglobulin as GvHD prophylaxis. 3. Alentuzumab as GvHD prophylaxis. 3\. Sirolimus as GvHD prophylaxis. 4\. HIV positive, HVC, HVB active or latent at HSCT. 5\. CMV prophylaxis with letermovir. \-