A Food-Effect Study of BPI-16350 in Healthy Subjects

Inclusion Criteria: * Healthy subjects aged 18\~45 (including 18 and 45 years old); * Male body weight ≥ 50kg, female body weight ≥ 45kg, body mass index (BMI) within the range of 19 \~ 26kg /m2; * Clinical laboratory evaluations within the reference range for the test laboratory, unless deemed not clinically significant by the Investigator; * The subjects should took effective contraceptive measures voluntarily from informed consent until 3 months after Study Completion； * Able to comprehend and willing to sign an informed consent form. Exclusion Criteria: * History of significant hypersensitivity to any drug compound or food； * Significant history or clinical manifestation of any significant cardiovascular, hepatic, renal, pulmonary, gastrointestinal, neurological, metabolic, musculoskeletal,hematological disorder； * Hepatitis B virus surface antigen, hepatitis C virus antibody, treponema pallidum antibody or human immunodeficiency virus antibody is positive； * Family history of long QTc syndrome; History or presence of an abnormal ECG； * Drug abusers, smokers or alcoholics； * Use of any medications within 14 days prior to the first administration； * Donation of blood ≥ 200 mL or receipt of blood products within 3 months before enrollment, or plan on blood donation during the study period； * Participation in any other investigational drug study or receive any vaccine within 3 months before enrollment； * Female subjects who are pregnant or lactating；the serum HCG test of women with fertility is postive at Screening.