This study tested the hypothesis that acute exposure to light during nighttime sleep adversely affects cardiometabolic function.
This study tested the hypothesis that acute exposure to light during sleep adversely affects next morning glucose homeostasis and whether this effect occurs via reduced sleep quality, melatonin suppression, or sympathetic nervous system (SNS) activation during sleep. Twenty young adults participated in this parallel-group study design. The room light condition (n=10) included one night of sleep in dim light (\< 3 lux) followed by one night of sleep with overhead room lighting (100 lux). The dim light condition (n=10) included two consecutive nights of sleep in dim light.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
20
The room light condition (n=10) included one night of sleep in dim light (\< 3 lux) followed by one night of sleep with overhead room lighting (100 lux). The dim light condition (n=10) included two consecutive nights of sleep in dim light.
Matsuda Index
OGTT
Time frame: Day 2
Matsuda Index
OGTT
Time frame: Day 3
HOMA-IR
Fasting
Time frame: Day 2
HOMA-IR
Fasting
Time frame: Day 3
Sleep Stages
Stage N1, N2, N3
Time frame: Night 1
Sleep Stages
Stage N1, N2, N3
Time frame: Night 2
Sleep Stages
Stage N1, N2, N3
Time frame: Night 3
Heart Rate
beat to beat
Time frame: Night 2
Heart Rate
beat to beat
Time frame: Night 3
Blood pressure
diastolic/systolic
Time frame: Day 2
Blood pressure
diastolic/systolic
Time frame: Day 3
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Slow Wave Activity
Spectral power in the Slow Wave Activity (0.5 to 4 Hz)
Time frame: Night 1
Slow Wave Activity
Spectral power in the Slow Wave Activity (0.5 to 4 Hz)
Time frame: Night 2
Slow Wave Activity
Spectral power in the Slow Wave Activity (0.5 to 4 Hz)
Time frame: Night 3