Ultrasound Guided Steroids Injection Versus PRP for Shoulder Pain Relief

Early Phase 1CompletedNCT05317624

Alexandria University60 enrolled

Overview

Comparison between effects of ultrasound guided platelet rich plasma injection versus steroids injection for pain relief in cases of partial rotator cuff tears

The effect of injection of platelet rich plasma will be compared with effects of steroids injection according to pain relief effects,, Side effects ,, healing ability ,, recurrence in both groups. 30 patient in each group will be included

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Shoulder Pain

Interventions

Platelet rich plasmaCOMBINATION_PRODUCT

platelet rich plasma will be obtained from the particepants own blood mixed with activator and bupivacaine

MethylprednisoloneCOMBINATION_PRODUCT

1ml methyl prednisolone 40mg\\ml mixed with normal saline and bupivacaine

Eligibility

Sex: ALLMin age: 20 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients with positive tests for rotator cuff pain 2. Patients with positive radiological (US or MRI) findings of partial rotator cuff tear Exclusion Criteria: 1. Patient refusal 2. Age less than 20 years. 3. Infection at injection site. 4. Prior surgery on the shoulder joint area. 5. Presence of other associated pathology in the shoulder joint 6. Patients using antiplatelet drugs (aspirin). 7. Contraindications to the use of platelet concentrate 8. Contraindications to the steroids injection

Locations (1)

Facility of medicine

Alexandria, Egypt

Outcomes

Primary Outcomes

Shoulder pain assesment

The pain will be assessed using visual analogue scale( score range=0-10,less than 4,4-6 and more than 6 for mild, moderate and severe pain respectively)

Time frame: 4 months

Secondary Outcomes

Assesment of rotator cuff tendon healing

assesment healing process of tendon using ultrasound technique

Time frame: 4 months

Assesment the failure rate after shoulder joint injection

failure of relief the symptoms after shoulder joint injection will be recorded

Time frame: 4 months

The reinjection rate recording

the incidence of reinjection the shoulder joint due to inadequate pain relief will be recorded

Time frame: 4 months

Assesment the rate of tear recurrence after shoulder joint injection

The rate of tear recurrence after 4 months of injection will be assessed using MRI or US

Time frame: 4 months

Simple shoulder assessment test

Functional assessment of shoulder joint will be done using simple sholder assessment test 0= maximal disability 20% -40% = crippled 40% -60% = severe disability 60% -80% = moderate disability 100% = no disability

Time frame: 4 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.