Ocular Surface Disease and IOP Monitoring With Travoprost Without Conservatives

N/ACompletedNCT05319470

Democritus University of Thrace25 enrolled

Overview

Primary objective of this study is to study the efficacy of travoprost without preservatives in the treatment of glaucoma patients and to monitor the ocular surface.

This is a prospective study including patients visiting the outpatient glaucoma clinic of the University General Hospital of Alexandroupolis for their standard evaluation. Study population is already under treatment with a travoprost preparation without preservatives. They will be fully informed about the procedure and the purpose of the study and a written consent will be obtained. For every patient included in the study intraocular pressure will be measured using a Goldman applanation tonometer, according to the standard way of practice at our clinic. Also, Tear Break-Up-Time (BUT), conjunctival hyperemia grading and Schirmer testing will be used to assess the ocular surface state. Visual field tests and OCT RNFL measurements will also be obtained. The above measurements will be repeated 6 months after the initial examination.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Glaucoma Glaucoma; Drugs Ocular Surface Disease

Interventions

Intraocular pressure (IOP)DIAGNOSTIC_TEST

Measurement of intraocular pressure in both eyes of the study population using the Goldman applanation tonometer.

Tear Break-up Time (TBUT)DIAGNOSTIC_TEST

TBUT will be calculated after instillation of a drop of fluorescein dye, by slit lamp biomicroscopy.

Conjuctival HyperemiaDIAGNOSTIC_TEST

Conjunctival hyperemia will be assessed by slit lamp biomicroscopy using a validated grading system.

Eligibility

Sex: ALLMin age: 35 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with glaucoma treated with travoprost without preservatives. Exclusion Criteria: * Co-administration of another anti-glaucoma preparation with or without preservatives, Sjogren's syndrome, poor eyelid occlusion of any etiology.

Locations (1)

Department of Ophthalmology, University Hospital of Alexandroupolis

Alexandroupoli, Evros, Greece

Outcomes

Primary Outcomes

Intraocular Pressure (IOP)

Intraocular pressure measurement in both eyes using the Goldman applanation tonometer.

Time frame: 6 months

Ocular Surface Disease

Tear breakup time (TBUT), conjuctival hyperemia scoring and Schirmer testing will be used to assess the ocular surface state of the study population.

Time frame: 6 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.