This optional sub study is a part of the phase 1b, Open-Label Study is to assess the safety, efficacy of miricorilant in patients with presumed Nonalcoholic Steatohepatitis (NASH)
This optional sub study is a part of the phase 1b, Open-Label Study is to assess the safety, efficacy of miricorilant in patients with presumed Nonalcoholic Steatohepatitis (NASH). All patients who participated in the current study (CORT118335-861) or the Corcept Phase 2a NASH study (CORT118335-860), and who received at least one dose of miricorilant will be eligible for participation in an observational follow-up study; this includes patients who either terminated early or are study completers.
Study Type
OBSERVATIONAL
Enrollment
22
Magnetic Resonance Imaging Proton Density Fat Fraction (MRI-PDFF) is a MRI-based diagnostic imaging biomarker of the liver.
Site 207
Chandler, Arizona, United States
Site 209
Tucson, Arizona, United States
Site 214
Panorama City, California, United States
Site 233
Santa Ana, California, United States
Change in liver-fat content assessed by MRI-PDFF after the last dose of study drug.
Time frame: Baseline Day 1 up to Month 12
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Site 211
Austin, Texas, United States
Site 213
Edinburg, Texas, United States
305
Houston, Texas, United States
Site 212
San Antonio, Texas, United States
226
Seattle, Washington, United States