The aim of the current study is to determine the effect of time of day on the muscle and metabolic responses to resistance exercises in obese or overweight adults. To achieve this aim we have the following objectives: 1. Compare the effects of resistance exercise training performed in the morning vs the evening on insulin sensitivity 2. Compare the effects of resistance exercise training performed in the morning vs the evening on gains in muscle mass and strength 3. Compare the acute glucose responses to resistance exercise performed in the morning vs the evening
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
36
Exercise will consist of 1 set x 9 exercises x 3 sessions per week x 6 weeks. The load to be used during training will be calculated as 80% of one-repetition maximum (1RM) with each set performed to failure. 1RM will be re-tested on week 3, and the load adjusted accordingly, and upon completion of the study. During the training period, all sessions of training will be supervised by the researcher. The following exercises will be performed: Bench press, biceps curl, lat pull down, overhead press, lateral raise, leg extension, leg curl and calf raise.
Stuart Robert Gray
Glasgow, United Kingdom
Change in insulin sensitivity
Insulin sensitivity calculated via the Matsuda Index during an oral glucose tolerance test
Time frame: Change from baseline to 6 weeks
Change in vastus lateralis muscle thickness
Muscle thickness of the vastus lateralis muscle measured via ultrasound
Time frame: Change from baseline to 6 weeks
Change in whole body lean mass
whole body lean mass measured via bio-electrical impedance
Time frame: Change from baseline to 6 weeks
Change in whole body fat mass
whole body fat mass measured via bio-electrical impedance
Time frame: Change from baseline to 6 weeks
Change in one-repetition maximum muscle strength
Sum of one-repetition maximum of Bench press, biceps curl, lat pull down, overhead press, lateral raise, leg extension, leg curl and calf raise exercise
Time frame: Change from baseline to 6 weeks
Change in knee extensor maximal isometric torque
Knee extensor maximal isometric torque measured during a maximal voluntary contraction
Time frame: Change from baseline to 6 weeks
Change in grip strength
Grip strength measured with a hand held dynamometer
Time frame: Change from baseline to 6 weeks
Change in mean glucose levels
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Mean glucose levels measured via continuous glucose monitors
Time frame: Change from baseline to 6 weeks
Change in glucose variability
Glucose variability measured via continuous glucose monitors
Time frame: Change from baseline to 6 weeks