Acute respiratory infections (such as influenza-like illness and upper respiratory tract infection) and acute infectious diarrhea are, for the most part, conditions that do not require medical management or specific treatment. Depending on the level of their transmission in the community, however, these diseases place significant clinical and financial burden on the healthcare system, particularly on emergency departments (ED). The investigators propose a prospective multicenter cohort study with which they aim to validate clinical decision rules combining 1) rapid molecular tests and 2) risk stratification tools to identify patients at low risk for complications related to acute respiratory infection and acute infectious diarrhea. The use of these clinical decision rules by nurses in ED triage could allow low-risk patients to be sent directly home for self-treatment without having to see the emergency physician. By eliminating the need for physician assessment, paraclinical testing and prolonged waiting in the ED, these triage-based clinical decision rules could provide a new, safe care pathway for acute respiratory infections and acute infectious diarrhea, reducing the burden on the patient, the healthcare system, and society.
Study Type
OBSERVATIONAL
Enrollment
1,474
Centre hospitalier universitaire de Montréal
Montreal, Quebec, Canada
Hôpital Général Juif
Montreal, Quebec, Canada
CHU de Québec - Université Laval
Québec, Canada
7- and 30-day combined incidence of ED returns, hospitalizations, and deaths.
Combined proportion incidence at 7 and 30 days after the initial visit of ED returns, hospitalizations and deaths related to acute respiratory infection or acute infectious diarrhea (obtained from provincial administrative databases).
Time frame: 30 days
Incidence proportion of ED returns
Incidence proportion of ED returns at 7 and 30 days after the initial visit.
Time frame: 30 days
Incidence of prescribing antiviral medication
Incidence of prescribing antiviral medication (e.g., oseltamivir) at the initial ED visit and at 7 days (telephone follow-up).
Time frame: 7 days
Incidence of antibiotic prescribing
Incidence of antibiotic prescribing at initial visit and at 7 days (telephone follow-up).
Time frame: 7 days
Incidence of intensive care unit admission
Incidence of intensive care unit admission at 30 days (obtained from provincial administrative database on hospital admissions).
Time frame: 30 days
Mean costs of care of the initial ED visit from a health system perspective
Mean costs of the initial ED visit from a health system perspective estimated using time-driven activity-based costing (data obtained from initial visit data collection, electronic medical records and provincial physician billing database).
Time frame: 30 days
Mean costs of the disease from the patient perspective
Mean 7-day costs from the patient perspective (obtained from the Cost for Patient Questionnaire - the CoPaQ- administered at telephone follow-up).
Time frame: 7 days
Length of stay in the ED
Length of stay in the ED on the initial visit (electronic medical records).
Time frame: Measured from ED arrival to ED discharge on the initial visit (maximum 120 hours)
Incidence proportion of hospitalizations
Incidence proportion of hospitalizations at 7 and 30 days after the initial visit.
Time frame: 30 days
Incidence proportion of deaths
Incidence proportion of deaths at 7 and 30 days after the initial visit.
Time frame: 30 days
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