In this study, the investigators compared the improvement of liver reserve function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal disconnection. To determine whether surgical treatment can help enhance postoperative liver reserve function and improve patient prognosis.
The patients were enrolled according to the research criteria, and collected the general basic information of the patients. After the preoperative preparation was perfected, the same surgical team performed laparoscopic splenectomy and azygoportal disconnection, and the same nursing team performed the nursing after the operation. Then, patients received a unified treatment plan after surgery, including medication, other treatments and follow-up. During the treatment, the liver reserve function related indicators of the patients were monitored before surgery, 3, 6, 12 and 24 months after surgery, including TBIL, DBIL, ALB, ALT, INR, PT, Child-Pugh, ascites, prealbumin, ICG-K, ICG-R 15 and ICG-T/2.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
20
The laparoscopic splenectomy and azygoportal disconnection was performed by the same surgical team.
Clinical Medical College of Yangzhou University
Yangzhou, Jiangsu, China
RECRUITINGLiver reserve function ICG-K at 3 months after surgery.
The level of liver reserve function ICG-K at 3 months after surgery.
Time frame: 3 months
Liver reserve function ICG-K at 6 months after surgery.
The level of liver reserve function ICG-K at 6 months after surgery.
Time frame: 6 months
Liver reserve function ICG-K at 12 months after surgery.
The level of liver reserve function ICG-K at 12 months after surgery.
Time frame: 12 months
Liver reserve function ICG-K at 24 months after surgery.
The level of liver reserve function ICG-K at 24 months after surgery.
Time frame: 24 months
Liver reserve function ICG-R 15 at 3 months after surgery.
The level of liver reserve function ICG-R 15 at 3 months after surgery.
Time frame: 3 months
Liver reserve function ICG-R 15 at 6 months after surgery.
The level of liver reserve function ICG-R 15 at 6 months after surgery.
Time frame: 6 months
Liver reserve function ICG-R 15 at 12 months after surgery.
The level of liver reserve function ICG-R 15 at 12 months after surgery.
Time frame: 12 months
Liver reserve function ICG-R 15 at 24 months after surgery.
The level of liver reserve function ICG-R 15 at 24 months after surgery.
Time frame: 24 months
Liver reserve function ICG-T/2 at 3 months after surgery.
The level of liver reserve function ICG-T/2 at 3 months after surgery.
Time frame: 3 months
Liver reserve function ICG-T/2 at 6 months after surgery.
The level of liver reserve function ICG-T/2 at 6 months after surgery.
Time frame: 6 months
Liver reserve function ICG-T/2 at 12 months after surgery.
The level of liver reserve function ICG-T/2 at 12 months after surgery.
Time frame: 12 months
Liver reserve function ICG-T/2 at 24 months after surgery.
The level of liver reserve function ICG-T/2 at 24 months after surgery.
Time frame: 24 months
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