To investigate the Influence of Climatic and Environmental Factors on Respiratory or Allergic Diseases in Sanya.
The study is an observational research, which will recruit the community migratory old people and children at school using cluster sampling in Sanya by Sanya Maternal and Child Health Care Hospital (Sanya Women and Children's Hospital). Sanya Central Hospital(Hainan Third People's Hospital) and People's Hospital of Sanya will assist to diagnose old people disease. The data of climate and environment will be obtained from Sanya Meteorological Administration and Sanya Municipal Ecology and Environment Bureau. 1. The primary purpose is to investigate the influence of the unique tropical climate and environmental factors on the migratory old people with diseases such as asthma, allergic rhinitis, COPD or atopic dermatitis in Sanya from northern China, and to provide scientific evidence for publicity of the tourism and the health care industry. 2. The secondary purpose is to investigate prevalence and risk factors of asthma, allergic rhinitis and atopic dermatitis among children in Sanya, which will provide a base for prevention and control strategies. 3. The third purpose is to retrospectively analyze the influence of climate and environmental factors in Sanya on children with asthma, allergic rhinitis and atopic dermatitis in the past decade, and a comparative analysis of the incidence on children in Sanya and Shanghai.
Study Type
OBSERVATIONAL
Enrollment
800
Sanya have unique island climate and environment campared with the north of China, with a feature of warm, moist and long-sunshine.
Sanya Women and Children's Hospital, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University
Sanya, Hainan, China
RECRUITINGThe difference of migratory old people with asthma, COPD, allergic rhinitis or atopic dermatitis between winter-spring season in tropical Sanya, Hainan Island and summer-autumn season in northeast China.
The asthma, COPD, allergic rhinitis or atopic dermatitis will be diagnosed and assessed through history of diseases and questionnaire..
Time frame: 3 year
Asthma control of migratory old people with asthma.
Quality of life is assessed through questionnaires of "Asthma Control Questionnaire (ACQ) ".
Time frame: 1-3 year
Asthma life quality of migratory old people with asthma.
Quality of life is assessed through questionnaires of "Asthma Quality of Life Questionnaire (AQLQ)".
Time frame: 1-3 year
Lung function of migratory old people with asthma or COPD.
Lung function is assessed through simple lung function test using spirometry.
Time frame: 1-3 year
The respiratory function of migratory old people with COPD.
Lung function is assessed through Saint George Respiratory Questionnaire (SGRQ).
Time frame: 1-3 year
Allergens will be detected in migratory old people with asthma, allergic rhinitis or atopic dermatitis.
Veinal blood was extracted to detect allergens.
Time frame: 1-3 year
Inflammatory factors will be detected in migratory old people with asthma, allergic rhinitis or atopic dermatitis.
Inflammatory factors such as esophageal granulocytes and eosinophils will be detected to assess inflammatory status of the migratory old people.
Time frame: 1-3 year
The change of asthma incidence rate in migratory old people .
Diagnosis and severity grading of asthma is based on the "American Thoracic Society" or the "National Heart, Lung, and Blood Institute guidelines."
Time frame: 1-3 year
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