Effects of Ramadan Fasting on Endothelial Function

University of Monastir250 enrolled

Overview

Include participants who intend to practice Ramadan fasting and accept to complete the three part of the study .

All volunteers and stable patients that intend to fast ramadan. Each participant is examined during three separate visits. 1. The week before Ramadan (Pre-R). 2. the last week of Ramadan (R). 3. the last week of the month following Ramadan (Post-R). Participants that miss one appointement or more are exluded from the study. Patient recrutement is conducted in primary care centers of the state of Monastir, out-patients clinic (Cardiology, Endocrinology) at the emergency department of Fattouma Bourguiba university hospital after a clarified written consent. All patients benifit of an endothelial peripheral arterial tonometry (Endo-PAT) test .

Study Type

OBSERVATIONAL

Enrollment

250

Conditions

Fasting Endothelial Dysfunction

Interventions

Reactive hyperemia-peripheral arterial tonometry Index (RHI )DIAGNOSTIC_TEST

RHI was assessed by RH-PAT using the EndoPAT2000 system .

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patient intending to fast Ramadan. Exclusion Criteria: * Age \< 18 years old * Hemodynamic instability. * Myocardial infarction requiring urgent revascularization. * Parkinsonism: tremor problem. * Refusal, communication problem.

Locations (1)

University hospital Fattouma Bourguiba

Monastir, Tunisia

Outcomes

Primary Outcomes

Change in Reactive Hyperemia Index (RHI)

RHI is calculated for each participant in the day of iclusion , then it is recalculated in the two others visits.

Time frame: the day of inclusion , 10 last day of Ramadan , 1 month after Ramadan

Data from ClinicalTrials.gov

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