Virtual Reliability System for Visual Spatial Attention Evaluation in Stroke Patients

National Taiwan University Hospital

Overview

The researchers designed a software based on a head-mounted displays for virtual reality (HMD-VR) to evaluate the reaction time to stimuli presented at right or left visual field. The study will recruit 100 stroke patients with hemisphere lesions (50 patients for right and left each) and 100 age-matched healthy controls. The participants will conduct a simple reaction time task in VR, with stimuli designated in the left or right hemi-field. The stroke patients will also received traditional tests for hemi-neglect. Test-retest reliability of the assessment will be conducted in a subset of the control group. The stroke patients will be followed in 3-4 weeks.

The researchers designed a software based on a head-mounted displays for virtual reality (HMD-VR) to evaluate the reaction time to stimuli presented at right or left visual field. The study will recruit 100 stroke patients with hemisphere lesions (50 patients for right and left hemisphere each) and 100 age-matched healthy controls. The participants will conduct a simple reaction time task in VR, with stimuli designated in the left or right hemi-field. The stroke patients will also receive traditional tests for hemi-neglect. The researchers will also collect the demographic data, cognition function and daily activity function. Test-retest reliability of the assessment will be conducted in a subset of the control group. The stroke patients will be followed in 3-4 weeks. The researchers will compare the results of a traditional hemi-neglect tests and VR-based tests and their changes in two occasions.

Study Type

OBSERVATIONAL

Conditions

Stroke Sequelae Neglect, Hemispatial

Eligibility

Sex: ALLMin age: 20 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria for stroke patients: 1. aged at least 20 years old 2. diagnosed with stroke involving unilateral MCA and ACA territory 3. with unilateral upper limb with normal function 4. neurologically and medically stable. Inclusion criteria for control group: 1\) healthy adults, age-matched to stroke patients Exclusion Criteria for both groups: 1. with history of neurological or psychiatric conditions other than stroke; 2. significant cognitive or speech problems that cause difficulties to cooperate with testing; 3. significant visual problems (such as color blindness, visual loss, cataract, glaucoma or other major eye condition) 4. upper limb musculoskeletal disorders to cause difficulties to use the keyboard or controller; 5. history of seizure, vestibular dysfunction or vertigo 6. can't tolerate HMD-VR

Locations (1)

National Taiwan University Hospital

Taipei, Taiwan

Outcomes

Primary Outcomes

reaction time

reaction time to the stimuli presented in the right or left hemi-field with VR software

Time frame: 4 weeks

hemineglect tests

Paper-based behavior inattention test (BIT)

Time frame: 4 weeks

Secondary Outcomes

ADL

activities of daily living function evaluated by barthel index

Time frame: 4 weeks

cognition

using Montreal Cognitive Assessment (MoCA)

Time frame: 4 weeks

cybersickness

using Simulator Sickness Questionnaire (SSQ)

Time frame: 1 day

Data from ClinicalTrials.gov

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