The Combination of Prednisone and Recombinant Human Thrombopoietin for Treatment of Immune Thrombocytopenia in Pregnancy

Inclusion Criteria: 1. Age 18-49; 2. Gestational weeks ≥20 weeks; 3. Platelet count \<30×10\^9/L, accompanied with or without bleeding symptoms; 4. Confirmed diagnosed, treatment-naive ITP in pregnancy; 5. Willing and able to sign written informed consent. Exclusion Criteria: 1. Secondary ITP such as drug-related thrombocytopenia; 2. Thrombocytopenia caused by viral infection (HIV, hepatitis B or hepatitis C); Other autoimmune diseases (including positive anti-nuclear antibodies, positive anti-cardiolipin antibodies, positive lupus anticoagulant factors, and positive Coombs) with severe heart, kidney, liver or respiratory dysfunction; 3. Severe immunodeficiency; 4. Myelodysplastic or myeloid fibrosis; 5. History of malignancy.