Polydextrose for Patients With Chronic Kidney Disease

Universidade Federal Fluminense40 enrolled

Overview

Constipation is a common complication in patients with chronic kidney disease (CKD), especially in hemodialysis (HD) patients. Reduced intake of fibre-rich food is among the most important causes of constipation. The study aims to investigate the possible influence of polydextrose (PDX) supplementation on constipation in patients with CKD on HD.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Chronic Kidney Diseases Constipation

Interventions

PolydextroseDIETARY_SUPPLEMENT

Administration of 3g polydextrose per day, for 2 months

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of Chronic Kidney Disease * Hemodialysis patients for more than 6 months * Aged 18 years or older Exclusion Criteria: * Patients pregnant * Smokers * Using antibiotics in the last 3 months * Autoimmune diseases * Clinical diagnosis of infectious diseases * Clinical diagnosis of Cancer * Clinical diagnosis of AIDS

Locations (1)

Denise Mafra

Rio de Janeiro, Rio de Janeiro, Brazil

Outcomes

Primary Outcomes

Change constipation status after supplementation with polydextrose

Stool frequency and Bristol Stool Form

Time frame: 2 months

Change in cytokines plasma levels measured by ELISA after supplementation with polydextrose

cytokines levels

Time frame: 2 months

Data from ClinicalTrials.gov

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