Currently, there is a paucity of quality research within the field of health science with a focus on persons with intellectual disabilities, and especially how longer lasting periods of varied physical activity affects the target group. There is a lack of insight, in how persons with intellectual disabilities learns and retains movement skills. Thus, the research group behind this project will investigate the following research questions: 1. Does 40 weeks of intense and varied sports and physical activities as an intervention lead to positive changes in health status for adults with intellectual disabilities? 2. Can lasting effects be measured three and six months after the intervention? 3. Does the intervention improve the motor competences for the participants? 4. How does defined groups of adult persons with Down syndrome and Cerebral Palsy learn and retain a new motor skill?
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
85
2 hours of physical activity per day, 5 days per week, for the intervention period
Department of Nutrition, Exercise and Health, University of Copenhagen
Copenhagen, Capital Region of Denmark, Denmark
Change in body weight
Body weight in kilograms
Time frame: Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Change in body fat mass
Body fat mass in kilograms
Time frame: Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Change in lean mass
Lean body mass in kilograms
Time frame: Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Change in fat free mass
Fat free mass in kilograms
Time frame: Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Change in cardiovascular fitness
Change in heart rate during the same absolute submaximal exercise intensity
Time frame: Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Change in areal bone mineral density of the whole body
Areal bone mineral density in grams per square centimeter (g/cm2) of the whole body
Time frame: Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Change in T-scores of the whole body
Whole body T-score. An arbitrary measure, describing the bone mineral density of the subjects relative to a reference value from 30 year old healthy persons.
Time frame: Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Change in areal bone mineral density of the lumbar spine (L1-L4)
Areal bone mineral density in grams per square centimeter (g/cm2) of the lumbar spine (L1-L4)
Time frame: Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Change in T-scores of the lumbar spine (L1-L4)
Lumbar spine (L1-L4) T-score. An arbitrary measure, describing the bone mineral density of the subjects relative to a reference value from 30 year old healthy persons.
Time frame: Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Change in areal bone mineral density of the bilateral femur regions
Areal bone mineral density grams per square centimeter (g/cm2) of the bilateral femur regions
Time frame: Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Change in T-scores of the bilateral femur regions
T-scores of the bilateral femur regions. An arbitrary measure, describing the bone mineral density of the subjects relative to a reference value from 30 year old healthy persons.
Time frame: Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Change in plasma bone turn-over marker (CTX)
Carboxy-terminal collagen crosslinks (CTX), measured as μg/L
Time frame: Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Change in Plasma bone turn-over marker (P1NP)
Procollagen type 1 N-terminal propeptide (P1NP), measured as μg/L
Time frame: Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
Plasma bone turn-over marker (Osteocalcin)
Osteocalcin, measured as μg/L
Time frame: Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks)
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