Comparison of Dexmedetomidine and Midazolam for Intra-op Sedation in TIVA in Children Undergoing Inguinal Hernia Repair

Sheikh Zayed Medical College185 enrolled

Overview

To compare dexmedetomidine and midazolam for intra-op sedation in TIVA in children undergoing inguinal hernia repair. The results of the study if found significant will guide the anesthetist in appropriate choice and dose of sedative drug with highest efficacy and minimum side effects to avoid post operative adverse effects associated with anesthesia

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

SINGLE

Enrollment

185

Conditions

Inguinal Hernia

Interventions

DexmedetomidineDRUG

Inj dexmedetomidine and inj midazolam given to 2 groups of participants and sedative effects of both drugs will be observed during surgery

MidazolamDRUG

Midazolam

Eligibility

Sex: ALLMin age: 12 MonthsMax age: 15 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Male and female paediatric patients In age range neonates to 15 years * Planned for elective inguinal hernia repair * Patients with uncomplicated hernia With ASA class I or II Exclusion Criteria: * Patients undergoing emergency inguinal repair * Patients with ASA class III,IV,V or VI * Patients present with complicated hernia * Patients with BMI above 40kg/m2 * Patients with any allergy to anesthesia * Patients with coagulopathy * Patients with narcotic/opioid addiction

Outcomes

Primary Outcomes

Level of sedation assessed through Ramsay Sedation Scale RSS

Time frame: 6 months

Central Contacts

Anab Farooqi, MBBS

CONTACT

03337923232 zaibanaab94@gmail.com

Data from ClinicalTrials.gov

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