The purpose of this study is to evaluate the drug levels of cendakimab delivered subcutaneously in healthy participants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
104
Specified Dose on Specified Days
Anaheim Clinical Trials Llc
Anaheim, California, United States
Maximum observed concentration (Cmax)
Time frame: Up to Day 105
Area under the concentration-time curve (AUC) from time zero to time of last quantifiable concentration (AUC(0-T))
Time frame: Up to Day 105
AUC from time zero extrapolated to infinite time (AUC(INF))
Time frame: Up to Day 105
Number of participants with treatment emergent adverse events (TEAEs)
Time frame: Up to Day 107
Number of Participants with Adverse Events (AEs)
Time frame: Up to Day 107
Number of participants with clinical laboratory abnormalities
Time frame: Up to Day 107
Number of participants with vital sign abnormalities
Time frame: Up to Day 107
Number of participants with physical examination abnormalities
Time frame: Up to Day 107
Number of participants with electrocardiogram (ECG) abnormalities
Time frame: Up to Day 107
Number of participants with concomitant medications
Time frame: Up to Day 107
Number of participants with concomitant procedures
Time frame: Up to Day 107
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Time of maximum observed concentration (Tmax)
Time frame: Up to Day 105
Terminal half-life (T-HALF)
Time frame: Up to Day 105
Apparent total body clearance (CL/F)
Time frame: Up to Day 105