A Systems Approach to Immunotherapy Biomarker Identification Within the Postoperative Wound-Healing Microenvironment in Patients With Gastroesophageal Cancer

Inclusion Criteria: * Patients undergoing esophagectomy or gastrectomy for gastroesophageal cancer. * Adult males and females at least 18 years of age * Ability to complete testing in the protocol and attend study visits * Able and willing to consent to protocol * Adequate organ function Absolute Neutrophil Count (ANC) ≥1.5 x 103/μL Platelets ≥100 x 103/μL Hemoglobin \>9.0 g/dL Total Bilirubin (\</= 2.0 mg/dl at time of Y90 radioembolization) AST/ALT ≤5 x upper limit of normal Albumin \>3 g/dL Creatinine ≤1.5 mg/dL Exclusion Criteria: * Female patients who are pregnant or breast-feeding * Concomitant illness that would prevent adequate patient assessment or in the investigators' opinion pose an added risk for study participants. * Life-threatening intercurrent illness * Anticipated poor compliance * Prisoners or subjects who are involuntarily incarcerated * Persons with decisional incapacity/cognitive impairment * Any history or evidence of severe illness or any other condition that would make the patient, in the opinion of the investigator unsuitable for the study * Subject is enrolled in a separate interventional clinical trial