Bio-ADM as a Biomarker of Refilling in Chronic Hemodialysis Patient

University Hospital, Montpellier150 enrolled

Overview

Aim of this study is to evaluate in a population of chronic kidney disease patients on dialysis (Stage 5D) the predictive value of bio-adrenomedullin (bio-ADM) level on vascular refilling rate.

Study Type

OBSERVATIONAL

Enrollment

150

Conditions

Chronic Kidney Disease 5D

Interventions

BioADM determination in plasmaBIOLOGICAL

BioADM determination in plasma

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion criteria: * Chronic Kidney Disease patient on dialysis (stage 5D) for more than 1 month * Anuric patient Exclusion criteria: * Patient protected by law * Patient under guardianship ou curatorship * Patient deprived of liberty

Locations (1)

UH Montpellier

Montpellier, France

RECRUITING

Outcomes

Primary Outcomes

Relationship between bio-ADM level and vascular refilling rate

The refilling rate will be assessed by the ratio of relative blood volume and UF max

Time frame: Day 1

Secondary Outcomes

Bio-ADM value according to comorbidity factors

Bio-ADM value according to comorbidity factors (diabetes, heart failure and low-grade inflammation)

Time frame: Day 1

Central Contacts

Jean-Paul CRISTOL, MD PhD

CONTACT

+33 467 338315 jp-cristol@chu-montpellier.fr

Marion MORENA CARRERE, PhD

CONTACT

+33 411 759893 m-morenacarrere@chu-montpellier.fr

Data from ClinicalTrials.gov

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