A cardiac arrest event has severe impact on the patient´s health-related quality of life. Survival of cardiac arrest does not innately translate to favorable quality of life. In particular, highly invasive resuscitation strategies, including extracorporeal cardio-pulmonary resuscitation (ECPR) due to therapy-refractory cardiac arrest, may have impact on long-term outcomes. Therefore, apart from acute medical treatment and physical rehabilitation, long-term effects on cardio-pulmonary, physical and neuro-psychiatric functions after cardiac arrest survival have to be evaluated and optimized. We plan to investigate a bundle of cardio-pulmonary, physical and neuro-psychiatric functions in patients who survived a therapy-refratory cardiac arrest with ECPR.
Study Type
OBSERVATIONAL
Enrollment
30
Charité - Universitätsmedizin Berlin
Berlin, Germany
Left ventricular ejection fraction (LVEF)
LVEF measured with transthoracic echocardiography.
Time frame: LVEF witihin one year after index cardiac arrest event.
Cognitive function
Cognitive function measured with a standardized questionnaire and following established scores: 1. Mini-mental-status-test \[0-30 points; higher score means better outcome\], 2. Cerebral Performance Categories Scale \[1-5; lower score means better outcome\].
Time frame: Cognitive function witihin one year after index cardiac arrest event.
Sign and symptoms of heart failure
Sign and symptoms of heart failure measured with a standardized questionnaire and following established score: European Quality of Life 5 Dimensions 3 Level Version \[0-100 points; higher score means better outcome\].
Time frame: Sign and symptoms of heart failure witihin one year after index cardiac arrest event.
Activity of daily living (ADL)
ADL measured with a standardized questionnaire and following estbalished score: Barthel index \[0-100 points; higher score means better outcome\].
Time frame: ADL witihin one year after index cardiac arrest event.
Comorbidity level
Comorbidity level measured with following established score: Charlson comorbidity index \[0-24 points; lower score means better outcome\].
Time frame: Comorbidity level witihin one year after index cardiac arrest event.
Number of cardiovascular medications
Number of cardiovascular medications documented with a standardized questionnaire.
Time frame: Number of cardiovascular medication witihin one year after index cardiac arrest event.
Cardiac stress test: Ergometry
Quantitative test to evaluate cardiopulmonary exercise tolerance and physical capacity by using a bicycle.
Time frame: Physical function witihin one year after index cardiac arrest event.
Cardiac stress test: Walking distance
Quantitative test to evaluate endurance and aerobic capacity by walking for six minutes (six minute walk test).
Time frame: Physical function witihin one year after index cardiac arrest event.
Vital function: Blood pressure
Non-invasive blood pressure measurement at rest (unit: mmHg).
Time frame: Blood pressure witihin one year after index cardiac arrest event.
Vital function: Electrocardiogram (ECG)
12-lead ECG measurement at rest.
Time frame: ECG activity witihin one year after index cardiac arrest event.
Vital function: Peripheral oxygen saturation
Peripheral oxygen saturation measurement at rest by using pulsoximetry (unit: percent).
Time frame: Peripheral oxygen saturation witihin one year after index cardiac arrest event.
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