Mailed FIT Outreach 2022

Abramson Cancer Center at Penn Medicine5,460 enrolled

Overview

This project aims to evaluate different approaches to increase colorectal cancer screening among primary care patients at Penn Medicine through a centralized screening outreach program. In a pragmatic trial, we will evaluate different approaches to increase response rate to mailed fecal immunochemical test (FIT) kits among eligible patients, including differentiated packaging, sending text reminders, and personalized reminders.

While colonoscopy procedures are recommended by guidelines for early detection of colorectal cancer, colonoscopy access remains limited due to delays in screening due to the pandemic and capacity issues. In this project, we will evaluate different ways of reaching out to eligible patients to encourage them to participate in colorectal cancer screening using fecal immunochemical testing (FIT). In a mailed FIT outreach campaign, we will compare user friendly packaging, text messaging, and personalized reminders to standard outreach with the goal of increasing colorectal cancer screening uptake.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

5,460

Conditions

Colorectal Cancer Colon Cancer

Interventions

Differentiated BoxBEHAVIORAL

Patients will receive mailed FIT kits in a box with differentiated packaging

Standard MailBEHAVIORAL

Patients will receive mailed FIT in a standard mailing envelope

TextBEHAVIORAL

Patients will receive a series of up to 3 texts explaining the importance of colon cancer screening and prompts to complete the mailed FIT.

Eligibility

Sex: ALLMin age: 50 YearsMax age: 74 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients ages 50-74 with Penn as preferred lab 2. Followed by Primary Care with a participating Penn Medicine PCP listed and at least one visit in the last 2 years 3. Not up to date on colorectal cancer screening per Health Maintenance (no colonoscopy in the last 10 years, stool testing in the last year, flexible sigmoidoscopy in the last 5 years, FIT-DNA in the last 3 years). Exclusion Criteria: 1. Personal or significant family history of CRC, colonic polyps, hereditary nonpolyposis colorectal cancer syndrome, familial adenomatous polyposis syndrome, other gastrointestinal cancer, gastrointestinal bleeding, iron-deficiency anemia, or inflammatory bowel disease 2. History of total colectomy, dementia or metastatic cancer 3. Currently on hospice or receiving palliative care 4. Uninsured or self-pay patients 5. Currently scheduled for a colonoscopy or sigmoidoscopy

Locations (1)

Penn Medicine

Philadelphia, Pennsylvania, United States

Outcomes

Primary Outcomes

FIT Completion

Percent of patients who complete FIT

Time frame: 4 months

Secondary Outcomes

FIT Completion

Percent of patients who complete FIT

Time frame: 6 months

Colorectal Cancer (CRC) Screening Completion (Any)

Percent of patients who complete any CRC screening

Time frame: 6 months

FIT Positive Follow-up Scheduling

Percent of patients with FIT+ results that schedule a colonoscopy

Time frame: 6 months

FIT Positive Follow-up Completion

Percent of patients with FIT+ results that complete a diagnostic colonoscopy

Time frame: 6 months

Data from ClinicalTrials.gov

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