Effects of Exercise Intervention on Muscle Strength in Severely Ill Patients

Taipei Veterans General Hospital, Taiwan60 enrolled

Overview

In recent years, due to the improvement in the survival rate of the intensive care unit, the problem of severe systemic fatigue (Intensive care unit acquired weakness; ICUAW) has continued to receive attention. Muscle mass decreases by 3-11% within a week, resulting in decreased muscle strength and muscle atrophy. Current studies suggest that ICUAW can lead to poorer function, prolonged ICU stay, and decreased quality of life. This study aimed to understand the muscle strength of critically ill patients and to explore the effect of exercise intervention on improving muscle strength. The experimental group received a four-week exercise bike intervention plus conventional rehabilitation exercises, while the control group received conventional rehabilitation exercises.

The content of the exercise is to use an exercise bike, start pedaling on the first day, time setting: 20 minutes, speed: 2, and adopt passive mode. If you can complete the exercise on the first day, the time will be adjusted to 30 minutes on the second day. If you cannot complete the exercise on the first day, the time will still start from 20 minutes on the second day. The maximum time is 30 minutes. If you can complete 30 minutes of passive exercise for 3 consecutive days, the fourth day will be adjusted to active exercise. The entire exercise training is seven days a week, once a day, once a 30-minute, at least 5 days. Those who were discharged to the general ward continued to complete this exercise training for up to 28 days. Stop exercising if heartbeat \> 140, mean arterial pressure \< 65, blood oxygen \< 90%, respiration \> 35 beats/min, or the patient requests to stop during exercise.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Interventions

exercise bikeOTHER

exercise is to use an exercise bike, start pedaling on the first day, time setting: 20 minutes, speed: 2, and adopt passive mode. If you can complete the exercise on the first day, the time will be adjusted to 30 minutes on the second day. If you cannot complete the exercise on the first day, the time will still start from 20 minutes on the second day. The maximum time is 30 minutes. If you can complete 30 minutes of passive exercise for 3 consecutive days, the fourth day will be adjusted to active exercise. The entire exercise training is seven days a week, once a day, once a 30-minute, at least 5 days. Those who were discharged to the general ward continued to complete this exercise training for up to 28 days.

Outcomes

Primary Outcomes

Basic Demographic Health Assessment Form

Age, sex, diagnosis, disease severity, reason for ICU admission

Time frame: baseline

days in intensive care unit

Health Assessment Form

Time frame: baseline

days on ventilator

Health Assessment Form

Time frame: baseline

total days in hospital

Health Assessment Form

Time frame: baseline

body mass index

Health Assessment Form

Time frame: baseline

level of albumin

Health Assessment Form

Time frame: baseline

The daily observation record sheet includes

Vital signs,respirator is used or not,bicycle use pattern,speed and time,reasons for stopping

Time frame: up to 28 days

Secondary Outcomes

Hand grip strength

Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength

Time frame: baseline(T0)

Hand grip strength

Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength

Time frame: 3 days after intervention(T1)

Hand grip strength

Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength

Time frame: 7 days after intervention(T2)

Hand grip strength

Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength

Time frame: 10 days after intervention(T3)

Hand grip strength

Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength

Time frame: 14 days after intervention(T4)

Hand grip strength

Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength

Time frame: 17 days after intervention(T5)

Hand grip strength

Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength

Time frame: 21 days after intervention(T6)

Hand grip strength

Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength

Time frame: 28 days after intervention(T7)

foot lift

Use a tape to measure foot lift

Time frame: baseline(T0)

foot lift

Use a tape to measure foot lift

Time frame: 3 days after intervention(T1)

foot lift

Use a tape to measure foot lift

Time frame: 7days after intervention(T2)

foot lift

Use a tape to measure foot lift

Time frame: 10days after intervention(T3)

foot lift

Use a tape to measure foot lift

Time frame: 14days after intervention(T4)

foot lift

Use a tape to measure foot lift

Time frame: 17ays after intervention(T5)

foot lift

Use a tape to measure foot lift

Time frame: 21days after intervention(T6)

foot lift

Use a tape to measure foot lift

Time frame: 28days after intervention(T7)

walking distance in 6 minutes