Remote ischemic preconditioning is one way to influence the success of therapy in cardiovascular patients. By means of remote ischemic preconditioning the incidence of atrial fibrillation after cardiac surgery was reduced by 54%. The investigators aim to investigate the effect of ischemic preconditioning in an easy-to-perform protocol with regard to the recurrence of atrial fibrillation after electrical cardioversion.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
240
Remote ischemic preconditioning through inflation of a blood pressure cuff to pressure values \> 200mmHg for 5 minutes followed by 5 minutes of reperfusion (3 times each) before electrocardioversion Electrical cardioversion for atrial fibrillation (100, 150, 200 Joule)
Inflation of a blood pressure cuff to pressure values \~ 10mmHg for 5 minutes followed by 5 minutes of reperfusion (3 times each) before electrocardioversion
St. Josefs-Hospital Wiesbaden
Wiesbaden, Hesse, Germany
Number of subjects with recurrence of atrial fibrillation 30 days after electrical cardioversion
Time frame: 30 days
Number of patients with short-term cardioversion success
Sinus rhythm lasting \> 30 seconds after electrocardioversion
Time frame: 30 seconds
Minimum energy required for successful electrocardioversion (in Joule)
Time frame: 30 days
Cumulative energy applied for successfull electrocardioversion (in Joule)
Time frame: 30 days
Cumulative number of shocks delivered for successfull electrocardioversion
Time frame: 30 days
Number of patients experiencing death from any cause, stroke /transient ischemic attack, relevant post-ECV arrhythmia and procedure-associated complications
Safety endpoint
Time frame: 30 days
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